Hmmm - another hot topic!
If your metering - well, if all else fails - read the instructions.

For those designing electronics - this is a whole new 'ballgame'.
Most things are going digital today - and it is very much 'throw away' technology - which is ironically meant to be cheap as well. Hmmm - that's the 'plan'.

As for the designing of circuits - be on your guard - and test your designs - and also the components that you chose to include in your boards.
Not all are the same - nor age as well as others.
Most tubes still require HV!!! (fingers) - and analog pick ups - along with a host of newer interfaces.
Keep your board designs and layouts accessible - safe from HV leads and fields ... keep your HV supplies _away_ from the digital components, and the anolog away from the digital parts.
As always - low noise design topologies - and testing of your prefab boards in SPICE or anything similar to iron out potential problems before spending $$$$.
Try to build it to look 'good' - that way it will last - and pot and cover your electronics and joints to keep potential contamination out.

Remember - HV means Electric field - which means particulate accumulation ... in that particular area.
Also, test things to destruction ... I know it is hard to see you work going through the mill - but its got to be done - and you'll learn from it.
No point someone a few years down the track getting dodgy gear because it was designed badly ... that is just stupid.
And lasty for those with microprocessors or DSPs - watch your coding!!!
Drop into assembler if you are writing in C or Java (or whatever) ... and get rid of that extra 'code' overhead - it causes problems!!!!
Your assembler should be neat, tidy, well written and '_bug free_' - this goes back to the above 'digital layout' designs!!!!
Your preboot power ups - or those that are continuously running should go through a fault 'mode' - and detect faults and then display or shut down!!

No one wants a potentially faulty or intermittent device because someone was lazy.