Wellll not really. Its more convoluted than the DCGL and area factors. Hence the hint on taking the additional training. If you notice after a while with MARSSIM techniques you will usually have no more than 25 samples for any MARSSIM project. 12-15 samples is typical, (seems a little low-look at the stdev of the scoping and MARSSIM results to see how they agree) and is not really dependent on DCGL, but the risk you wish to assume (alpha and beta), distribution design, variability, LLD, LBGR etc. The 100 samples will invoke the central limits theorm thus reducing the need for statistical schemes. 59 samples will provide a nice distribution showing that most sites are log normal and should be planned accordingly. The 12-15 samples you mention are the end of the road testing that results from limiting the decision unit size, adequate scoping surveys (lots of samples), limiting critical values, and a DCGL well below any level of concern for dose to the population.